![Blood-Brain Barrier in Drug Discovery](https://d3k2uuz9r025mk.cloudfront.net/media/image/58/30/d4/1711625283_355909908520_600x600.jpg)
Blood-Brain Barrier in Drug Discovery
Kurzinformation
![Natural](https://shop.studibuch.de/media/image/c4/23/50/Buch-Vorteil.png)
![Coins](https://shop.studibuch.de/media/image/74/b1/94/Lieferung-Vorteil.png)
![Check](https://shop.studibuch.de/media/image/a1/0b/2c/Muenzen-Vorteil.png)
inkl. MwSt. Versandinformationen
Artikel zZt. nicht lieferbar
Artikel zZt. nicht lieferbar
![Zahlungsarten](/media/image/d6/9c/c0/Payments.png)
Beschreibung
Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant - and most challenging - areas of drug discovery. * Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects * Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies * Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes * Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) * Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market
Produktdetails
![](https://stb-media.cstatic.io/media/image/b1/82/59/handgeprueftSiegel.png)
So garantieren wir Dir zu jeder Zeit Premiumqualität.
Über den Autor
- hardcover -
- Erschienen 1991
- VCH