
CNS Neuroprotection
Kurzinformation



inkl. MwSt. Versandinformationen
Artikel zZt. nicht lieferbar
Artikel zZt. nicht lieferbar

Beschreibung
"CNS neuroprotection" was a common subject of papers, symposia, and reviews during the previous "decade of the brain. " Indeed, in recent years, experimental study of putative neuroprotective agents prompted clinical trials of numerous drug candidates in acute and chronic human neurodegenerative conditions. While the outcomes of these trials have not been as successful as initially hoped, these were early explorations, and the pipeline of relevant ideas continues to grow in strength and depth. We predict that early in this new millennium, crippling disorders such as stroke and Alzheimer's disease will be treated effectively by therapeutic neuroprotective strategies. This volume of the Handbook of Experimental Pharmacology titled eNS Neuroprotection provides a pharmacological perspective on currently promis ing neuroprotective approaches, and a clinical perspective on the challenges involved in establishing the efficacy of these approaches through appropriate clinical trials. Section I, "Mechanistic Approaches to CNS Neuroprotection," reviews major injury mechanisms that have formed the basis for many past and present clinical trials conducted around the world. Dr. KIM and colleagues, Washington University School of Medicine, review the status of blocking excitotoxicity as an approach to CNS neuroprotection. Dr. WANG, Pfizer Global Research and Development,Ann Arbor Laboratories, outlines evidence supporting a contri bution of apoptosis to pathological neuronal or glial cell loss. Drs. BECKER and HALLENBECK, University of Washington and the National Institute on Neuro logical Diseases and Stroke, respectively, argue that inhibiting inflammatory pathways in the brain can be neuroprotective. Dr. von Marcoux, Frank W. und Choi, Dennis W.
Produktdetails

So garantieren wir Dir zu jeder Zeit Premiumqualität.
Über den Autor
- hardcover
- 735 Seiten
- Erschienen 2004
- Springer
- Gebunden
- 375 Seiten
- Erschienen 2011
- Wiley-VCH
- paperback
- 410 Seiten
- Erschienen 2007
- Thieme
- paperback
- 299 Seiten
- Erschienen 1994
- John Wiley & Sons Ltd
- paperback
- 424 Seiten
- Erschienen 2010
- Thieme
- Gebunden
- 234 Seiten
- Erschienen 2018
- Thieme
- Gebunden
- 234 Seiten
- Erschienen 2008
- Wiley-VCH
- Kartoniert
- 212 Seiten
- Erschienen 2022
- medhochzwei
- Kartoniert
- 480 Seiten
- Erschienen 2022
- Springer
- Kartoniert
- 464 Seiten
- Erschienen 2015
- Lippincott Williams and Wil...
- Hardcover
- 299 Seiten
- Erschienen 2006
- Thieme
- paperback
- 792 Seiten
- Erschienen 2008
- Springer