

The Mechanobiology of Obesity and Related Diseases
Kurzinformation



inkl. MwSt. Versandinformationen
Artikel zZt. nicht lieferbar
Artikel zZt. nicht lieferbar

Beschreibung
This volume describes the state-of-knowledge in the study of the relationships between mechanical loading states in tissues and common pathophysiologies related to increase in mass of adipose tissues and/or hyperglycemia which eventually lead to obesity, diabetes, insulin resistance, hyperlipidemia, metabolic inflammations, certain types of cancer and other related diseases. There appears to be an interaction between the loading states in tissues and cells and these chronic conditions, as well as with factors such as age, gender and genetics of the individual. Bioengineering has made key contributions to this research field in providing technologies for cell biomechanics experimentation, microscopy and image processing, tissue engineering and multi-scale, multi-physics computational modeling. Topics at the frontier of this field of study include: the continuous monitoring of cell growth, proliferation and differentiation in response to mechanical factors such as stiffness of the extracellular matrix (ECM) and mechanical loads transferred through the ECM; mechanically-activated signaling pathways and molecular mechanisms; effects of different loading regimes and mechanical environments on differentiation fates of mesenchymal stem cells (MSCs) into myogenic and osteogenic versus adipogenic lineages; the interactions between nutrition and mechanotransduction; cell morphology, focal adhesion patterns and cytoskeletal remodeling changes in adipogenesis; activation of receptors related to diabetes by mechanical forces; brown and white adipose plasticity and its regulation by mechanical factors. von Gefen, Amit und Benayahu, Dafna
Produktdetails

So garantieren wir Dir zu jeder Zeit Premiumqualität.
Über den Autor
- Gebunden
- 216 Seiten
- Erschienen 2010
- Springer
- hardcover
- 464 Seiten
- Erschienen 2022
- Wiley-Blackwell
- Hardcover
- 332 Seiten
- Erschienen 1997
- Humana
- Hardcover
- 116 Seiten
- Erschienen 2003
- Springer
- Hardcover
- 416 Seiten
- Erschienen 2023
- Wiley-Blackwell
- Gebunden
- 398 Seiten
- Erschienen 2010
- Wiley-Blackwell
- hardcover
- 386 Seiten
- Erschienen 2006
- Springer
- hardcover
- 336 Seiten
- Erschienen 2012
- Humana
- hardcover
- 784 Seiten
- Erschienen 2016
- Academic Press
- hardcover
- 352 Seiten
- Erschienen 1980
- Springer
- Gebunden
- 864 Seiten
- Erschienen 2011
- Hodder Arnold
- hardcover
- 152 Seiten
- Erschienen 2003
- UNI-MED
- Hardcover
- 316 Seiten
- Erschienen 2016
- Springer
- hardcover
- 452 Seiten
- Erschienen 2006
- Cambridge University Press
- hardcover
- 702 Seiten
- Erschienen 1987
- Cold Spring Harbor Laboratory
- Hardcover
- 308 Seiten
- Erschienen 2022
- MDPI AG
- Gebunden
- 346 Seiten
- Erschienen 2012
- Academic Press