Since the discovery of the bone morphogenetic proteins (BMPs) more than 15 years ago, there has been an unpredicted explosion of both basic scientific discoveries and clinical reports on their use from institutions all over the world....

Completing the PIR series, this volume summarizes the major advances made in the local and systemic use of bone morphogenetic proteins (BMPs). Chapters are dedicated to the regulation of BMP-signaling pathways; biological actions of BMPs...