Coarse-Grained Modelling of DNA and DNA Self-Assembly
Kurzinformation
Sprache:
Englisch
ISBN:
3642305164
Verlag:
Seitenzahl:
176
Auflage:
-
Erschienen:
2012-08-01
Beschreibung
Coarse-Grained Modelling of DNA and DNA Self-Assembly
This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker - the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology. von Ouldridge, Thomas E.
Produktdetails
Einband:
Gebunden
Seitenzahl:
176
Erschienen:
2012-08-01
Sprache:
Englisch
EAN:
9783642305160
ISBN:
3642305164
Verlag:
Gewicht:
453 g
Auflage:
-
Verwandte Sachgebiete:
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