Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery (Drug Discovery in Infectious Diseases)
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Beschreibung
"Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery" von Paul M. Selzer ist ein wissenschaftliches Werk, das sich mit der Biologie von Parasiten und deren Bedeutung für die Entwicklung neuer Medikamente gegen Infektionskrankheiten befasst. Das Buch bietet einen tiefgehenden Einblick in die Stoffwechselprozesse von Parasiten und untersucht, wie dieses Wissen genutzt werden kann, um innovative therapeutische Ansätze zu entwickeln. Es deckt eine Vielzahl von Themen ab, darunter die molekularen Mechanismen der Parasit-Wirt-Interaktionen, moderne Techniken zur Erforschung parasitärer Stoffwechselwege und die Identifizierung neuer Zielstrukturen für Arzneimittel. Darüber hinaus diskutiert das Buch aktuelle Fortschritte in der Wirkstoffforschung und -entwicklung sowie Herausforderungen und zukünftige Perspektiven im Kampf gegen parasitäre Erkrankungen. Es richtet sich an Forscher, Studenten und Fachleute auf dem Gebiet der Parasitologie und Infektionskrankheiten.
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Über den Autor
Volume Editors: Prof. Sylke Müller received her PhD in 1991 from the University of Hamburg. In 1992 she worked at the London School of Hygiene and Tropical Medicine, before returning to the Bernhard Nocht Institute for Tropical Medicine in Hamburg in 1994. In 1999 she was awarded the Habilitation and the venia legendi. From 2001 to 2012 she was funded by a Wellcome Trust Senior Fellowship at Dundee University (until 2004) and the University of Glasgow (2004 to 2012). In 2006 she was awarded a Personal Chair in Molecular and Biochemical Parasitology at the University of Glasgow. Prof. Rachel Cerdan received her PhD from the University of Paris XI in 1997. She spent three years at the Laboratory of Molecular Biology (Medical Research Council) in Cambridge, UK as a Marie Curie post-doctoral fellow. She then moved to the Centre of Structural Biochemistry in Montpellier, France. In 2003, she joined the laboratory of Dynamics of Membrane Interactions in Normal and Pathological Cells in Montpellier. Currently, she is professor in biochemistry and structural biology at the University of Montpellier, France. Her current projects focus on the biochemical and structural characterization of pharmacological targets to develop new classes of antimalarials. Prof. Ovidiu Radulescu studied physics and mathematics in Bucharest and Paris and obtained his PhD in 1994 from the University of Paris XI, France. Immediately after his PhD, he worked in theoretical condensed matter physics, first in the Institute of Theoretical Physics in Nijmegen, the Netherlands, and then in the Physics Department of the University of Leeds, UK. In 1999 he joined as a lecturer the Department of Mathematics of the University of Rennes 1, France. At that time, he was also associate member of the French Institute for Research in Computer Science and Automation, INRIA. Since 2009, he is Professor in Systems Biology and team leader at the University of Montpellier, France. His team is part of the laboratory DIMNP UMR5235, whose main focuses are in parasitology and immunology. Series Editor: Prof. Paul M. Selzer studied biology, parasitology, and biochemistry at the University of Tübingen, Germany, where he also received his PhD in biochemistry. He spent three years at the Molecular Design Institute and the Parasitology and Tropical Disease Research Laboratory at the University of California, San Francisco. During his career he has worked as a researcher and scientific manager for several pharmaceutical companies, and is currently Head of Antiparasitics R&D at Boehringer Ingelheim Animal Health, Germany. He is also a visiting professor at the Interfaculty Institute of Biochemistry of the University of Tübingen, and an honorary professor of the Department of Infection, Immunity, and Inflammation at the University of Glasgow, UK.
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