Nucleic Acids in Chemistry and Biology

Nucleic Acid in Chemistry and Biology 3rd edition, has been extensively updated from previous editions. Featuring an expanded group of editors and contributors this leading textbook offers a thorough background in all modern aspects of Nucleic Acid Chemistry and Biology. Coverage includes: - both the chemistry and biology of nucleic acids - the chemical synthesis of nucleosides and nucleotides - the chemistry for the synthesis of oligonucleotides and analogues This book provides sufficient chemical insight to satisfy the chemist and to provide an introduction for a molecular biologist and the essential aspects of the molecular biology of nucleic acids accessible to a chemist. TOC:Introduction and Overview.- DNA and RNA Structure.- Nucleosides and Nucleotides.- Synthesis of Oligonucleotides.- Nucleic Acids in Biotechnology.- Genes and Genomes.- RNA Structure and Function.- Covalent interactions of nucleic acids with small molecules and their repair.- Reversible small molecule-nucleic acid interactions.- Protein-nucleic acid interactions.- Physical and structural techniques applied to nucleic acids.- Subject Index.